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Analysis of Isoaspartic Acid by Selective Proteolysis with Asp-N and Electron Transfer Dissociation Mass Spectrometry

A ubiquitous yet underappreciated protein post-translational modification, isoaspartic acid (isoAsp, isoD or β-Asp), generated via the deamidation of asparagine or isomerization of aspartic acid in proteins, plays a diverse and crucial role in ageing, as well as autoimmune, cancer, neurodegeneration...

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Hlavní autoři: Ni, Wenqin, Dai, Shujia, Karger, Barry L., Zhou, Zhaohui Sunny
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936825/
https://ncbi.nlm.nih.gov/pubmed/20712325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101806e
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