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Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration

This review will discuss the formation and potential implications of 7-ketocholesterol (7KCh) in the retina. 7KCh is a proinflammatory oxysterol known to be present in high amounts in oxidized LDL deposits associated with atheromatous plaques. 7KCh is generated in situ in these lipoprotein deposits...

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Detalhes bibliográficos
Main Authors: Rodríguez, Ignacio R., Larrayoz, Ignacio M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936760/
https://ncbi.nlm.nih.gov/pubmed/20567027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R004820
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