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Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators

Complete folding is not a prerequisite for protein function, as disordered and partially folded states of proteins frequently perform essential biological functions. In order to understand their functions at the molecular level, we utilized diverse experimental measurements to calculate ensemble mod...

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Autori principali: Marsh, Joseph A., Dancheck, Barbara, Ragusa, Michael J., Allaire, Marc, Forman-Kay, Julie D., Peti, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936704/
https://ncbi.nlm.nih.gov/pubmed/20826336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.05.015
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