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Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear

Sensorineural deafness and balance dysfunction are common impairments in humans frequently caused by defects in the sensory epithelium of the inner ear, composed of hair cells and supporting cells. Lineage studies have shown that hair cells and supporting cells arise from a common progenitor, but ho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pan, Wei, Jin, Ying, Stanger, Ben, Kiernan, Amy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936630/
https://ncbi.nlm.nih.gov/pubmed/20733081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003089107
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