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Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance

Repetitive sequences in eukaryotic genomes induce chromatin-mediated gene-silencing of juxtaposed genes. Many components that promote or antagonize silencing have been identified, but how heterochromatin causes variegated and heritable changes in gene expression remains mysterious. We have used indu...

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Detalhes bibliográficos
Main Authors: Schneiderman, Jonathan I., Goldstein, Sara, Ahmad, Kami
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936522/
https://ncbi.nlm.nih.gov/pubmed/20838586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001095
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