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Local Therapy in BRCA1 and BRCA2 Mutation Carriers with Operable Breast Cancer: Comparison of Breast Conservation and Mastectomy

PURPOSE: Women with BRCA1 and BRCA2 mutations have an elevated risk of breast cancer and ovarian cancer, but also of developing second primary breast cancer. BRCA1/2 mutation carriers with breast cancer must choose between breast conservation (BCT) and mastectomy (M) yet data on outcomes are limited...

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Autors principals: Pierce, Lori J., Phillips, Kelly-Anne, Griffith, Kent A., Buys, Saundra, Gaffney, David K., Moran, Meena S., Haffty, Bruce G., Ben-David, Merav, Kaufman, Bella, Garber, Judy E., Merajver, Sofia D., Balmaña, Judith, Meirovitz, Amichay, Domchek, Susan M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936479/
https://ncbi.nlm.nih.gov/pubmed/20411323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0894-z
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