Female sex hormones mediate the allergic lung reaction by regulating the release of inflammatory mediators and the expression of lung E-selectin in rats

BACKGROUND: Fluctuations of estradiol and progesterone levels caused by the menstrual cycle worsen asthma symptoms. Conflicting data are reported in literature regarding pro and anti-inflammatory properties of estradiol and progesterone. METHODS: Female Wistar rats were ovalbumin (OVA) sensitized 1...

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Main Authors: de Oliveira, Ana Paula Ligeiro, Peron, Jean Pierre Schatzmann, Damazo, Amilcar Sabino, dos Santos Franco, Adriana Lino, Domingos, Helori Vanni, Oliani, Sonia Maria, Oliveira-Filho, Ricardo Martins, Vargaftig, Bernardo Boris, Tavares-de-Lima, Wothan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936382/
https://ncbi.nlm.nih.gov/pubmed/20735828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-115
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