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Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism

BACKGROUND: The mechanisms responsible for the cardiovascular mortality in type I diabetes (DM) have not been defined completely. We have shown in conscious dogs with DM that: 1) baseline coronary blood flow (CBF) was significantly decreased, 2) endothelium-dependent (ACh) coronary vasodilation was...

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Detalhes bibliográficos
Main Authors: Ojaimi, Caroline, Kinugawa, Shintaro, Recchia, Fabio A, Hintze, Thomas H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936363/
https://ncbi.nlm.nih.gov/pubmed/20735837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-43
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