A Large Study of Androgen Receptor Germline Variants and Their Relation to Sex Hormone Levels and Prostate Cancer Risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium

Background: Androgens are key regulators of prostate gland maintenance and prostate cancer growth, and androgen deprivation therapy has been the mainstay of treatment for advanced prostate cancer for many years. A long-standing hypothesis has been that inherited variation in the androgen receptor (A...

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Autors principals: Lindström, Sara, Ma, Jing, Altshuler, David, Giovannucci, Edward, Riboli, Elio, Albanes, Demetrius, Allen, Naomi E., Berndt, Sonja I., Boeing, Heiner, Bueno-de-Mesquita, H. Bas, Chanock, Stephen J., Dunning, Alison M., Feigelson, Heather Spencer, Gaziano, J. Michael, Haiman, Christopher A., Hayes, Richard B., Henderson, Brian E., Hunter, David J., Kaaks, Rudolf, Kolonel, Laurence N., Le Marchand, Loic, Martínez, Carmen, Overvad, Kim, Siddiq, Afshan, Stampfer, Meir, Stattin, Pär, Stram, Daniel O., Thun, Michael J., Trichopoulos, Dimitrios, Tumino, Rosario, Virtamo, Jarmo, Weinstein, Stephanie J., Yeager, Meredith, Kraft, Peter, Freedman, Matthew L.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936075/
https://ncbi.nlm.nih.gov/pubmed/20534771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1911
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