Signalling pathways involved in sildenafil-induced relaxation of human bladder dome smooth muscle

BACKGROUND AND PURPOSE: The mechanism(s) of action responsible for the beneficial effects of phosphodiesterase 5 (PDE5) inhibitors including sildenafil on lower urinary tract symptoms suggestive of benign prostate hyperplasia are unclear. In particular, the role of the NO-cGMP signalling pathway in...

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Detalhes bibliográficos
Main Authors: Oger, S, Behr-Roussel, D, Gorny, D, Lebret, T, Validire, P, Cathelineau, X, Alexandre, L, Giuliano, F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936023/
https://ncbi.nlm.nih.gov/pubmed/20590607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00748.x
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