A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood

BACKGROUND AND PURPOSE: Hydrogen sulphide (H(2)S) is a labile, endogenous metabolite of cysteine, with multiple biological roles. The development of sulphide-based therapies for human diseases will benefit from a reliable method of quantifying H(2)S in blood and tissues. EXPERIMENTAL APPROACH: Conce...

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Main Authors: Wintner, Edward A, Deckwerth, Thomas L, Langston, William, Bengtsson, Asa, Leviten, Dina, Hill, Paul, Insko, Michael A, Dumpit, Ronald, VandenEkart, Emily, Toombs, Christopher F, Szabo, Csaba
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2010
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936000/
https://ncbi.nlm.nih.gov/pubmed/20590590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00704.x
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