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Impairment of endothelial SK(Ca) channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats

BACKGROUND AND PURPOSE: Previous studies have shown that endothelium-dependent hyperpolarization of myocytes is reduced in resistance arteries from spontaneously hypertensive rats (SHRs). The aim of the present study was to determine whether this reflects down-regulation of endothelial K(+) channels...

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Détails bibliographiques
Auteurs principaux: Weston, AH, Porter, EL, Harno, E, Edwards, G
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935991/
https://ncbi.nlm.nih.gov/pubmed/20233221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00657.x
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