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A structure-activity relationship for induction of meningeal inflammation by muramyl peptides.

Components of bacterial peptidoglycans have potent biological activities, including adjuvant effects, cytotoxicity, and induction of sleep. Mixtures of peptidoglycan components also induce inflammation in the lung, subarachnoid space, and joint, but the structural requirements for activity are unkno...

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Bibliographic Details
Main Authors: Burroughs, M, Rozdzinski, E, Geelen, S, Tuomanen, E
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC293593/
https://ncbi.nlm.nih.gov/pubmed/8325996
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