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Mutational Profiling of Kinases in Human Tumours of Pancreatic Origin Identifies Candidate Cancer Genes in Ductal and Ampulla of Vater Carcinomas

BACKGROUND: Protein kinases are key regulators of cellular processes (such as proliferation, apoptosis and invasion) that are often deregulated in human cancers. Accordingly, kinase genes have been the first to be systematically analyzed in human tumors leading to the discovery that many oncogenes c...

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Bibliografiske detaljer
Main Authors: Corbo, Vincenzo, Ritelli, Rossana, Barbi, Stefano, Funel, Niccola, Campani, Daniela, Bardelli, Alberto, Scarpa, Aldo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935892/
https://ncbi.nlm.nih.gov/pubmed/20838624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012653
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