Locus category based analysis of a large genome-wide association study of rheumatoid arthritis

To pinpoint true positive single-nucleotide polymorphism (SNP) associations in a genome-wide association study (GWAS) of rheumatoid arthritis (RA), we categorize genetic loci by external knowledge. We test both the ‘enrichment of associated loci’ in a locus category and the ‘combined association’ of...

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Detalhes bibliográficos
Main Authors: Freudenberg, Jan, Lee, Annette T., Siminovitch, Katherine A., Amos, Christopher I., Ballard, David, Li, Wentian, Gregersen, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935861/
https://ncbi.nlm.nih.gov/pubmed/20639398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq304
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