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The Protein Kinase C Pathway Acts through Multiple Transcription Factors to Repress Gonadotropin-Releasing Hormone Gene Expression in Hypothalamic GT1–7 Neuronal Cells
The GnRH gene uses two well-defined regions to target expression to a small population of hypothalamic GnRH neurons: a 173-bp proximal promoter and a 300-bp enhancer localized at approximately −1800 to −1500 bp from the start site. Interaction of multiple factors with the GnRH enhancer and promoter...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935804/ https://ncbi.nlm.nih.gov/pubmed/15994198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2004-0463 |
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