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Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors

XAGE-1 is a cancer/testis (CT) antigen and has been shown to be immunogenic in lung cancer patients. Among 4 alternative splicing variants, XAGE-1a, b, c and d, XAGE-1b mRNA was dominantly expressed in cancer. In this study, we generated a XAGE-1b mAb, USO9-13. The B cell epitope recognized by the U...

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Detalhes bibliográficos
Main Authors: Sato, Shuichiro, Noguchi, Yuji, Ohara, Nobuya, Uenaka, Akiko, Shimono, Michihide, Nakagawa, Kazuhiko, Koizumi, Fumihito, Ishida, Toshiaki, Yoshino, Tadashi, Shiratori, Yasushi, Nakayama, Eiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Academy of Cancer Immunology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935747/
https://ncbi.nlm.nih.gov/pubmed/17335148
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