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dsRNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis
Adenosine deaminases acting on RNA (ADARs) catalyse hyper-editing of long dsRNAs, whereby up to 50% of adenosines are converted to inosine (I). While hyper-edited dsRNAs (IU-dsRNAs) have been implicated in various cellular functions, we now provide evidence suggesting a novel role. We show that IU-d...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935675/ https://ncbi.nlm.nih.gov/pubmed/20694008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1864 |
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