The Role of NADPH Oxidase 1–Derived Reactive Oxygen Species in Paraquat-Mediated Dopaminergic Cell Death

Oxidative stress is the common downstream effect of a variety of environmental neurotoxins that are strongly implicated in the pathogenesis of Parkinson's disease. We demonstrate here that the activation of NADPH oxidase 1 (Nox1), a specialized superoxide-generating enzyme complex, plays a key...

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Bibliografiske detaljer
Main Authors: Cristóvão, Ana Clara, Choi, Dong-Hee, Baltazar, Graça, Beal, M. Flint, Kim, Yoon-Seong
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2009
Fag:
Forum Original Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935343/
https://ncbi.nlm.nih.gov/pubmed/19450058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2459
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