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An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1
AMP-activated protein kinase (AMPK) is a master metabolic regulator for controlling cellular energy homeostasis. Its homolog in yeast, SNF1, is activated in response to glucose depletion and other stresses. The catalytic (α) subunit of AMPK/SNF1 in yeast (Snf1) contains a protein Ser/Thr kinase doma...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Union of Crystallography
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935214/ https://ncbi.nlm.nih.gov/pubmed/20823513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110028265 |
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