An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1

AMP-activated protein kinase (AMPK) is a master metabolic regulator for controlling cellular energy homeostasis. Its homolog in yeast, SNF1, is activated in response to glucose depletion and other stresses. The catalytic (α) subunit of AMPK/SNF1 in yeast (Snf1) contains a protein Ser/Thr kinase doma...

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Detaylı Bibliyografya
Asıl Yazarlar: Rudolph, Michael J., Amodeo, Gabriele A., Tong, Liang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2010
Konular:
Structural Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935214/
https://ncbi.nlm.nih.gov/pubmed/20823513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110028265
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