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A Simple Synthesis of Nitriles from Aldoximes1

[Image: see text] Easily synthesized aldoximes have been converted to the corresponding nitriles under very mild conditions by a simple reaction with 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and DBU in CH(2)Cl(2), THF or DMF. As an alternative reagent that eli...

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Détails bibliographiques
Auteurs principaux: Singh, Manish K., Lakshman, Mahesh K.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935138/
https://ncbi.nlm.nih.gov/pubmed/19301882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo900100v
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