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Structural Basis for the Transcriptional Regulation of Membrane Lipid Homeostasis
DesT is a transcriptional repressor that regulates the genes which control the unsaturated:saturated fatty acid ratio available for membrane lipid synthesis. DesT bound to unsaturated acyl-CoA has a high affinity for its cognate palindromic DNA-binding site, whereas DesT bound to saturated acyl-CoA...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935088/ https://ncbi.nlm.nih.gov/pubmed/20639888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1847 |
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