Baseline Genotypic and Phenotypic Susceptibilities of HIV-1 Group O to Enfuvirtide

We assessed the natural genotypic and phenotypic susceptibilities to enfuvirtide of 171 HIV group O (HIV-O) samples and 29 strains, respectively. The N42D resistance-associated mutation in the gp41 region was detected in 98% of cases. The phenotypic assay showed a wide range of baseline susceptibili...

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Bibliographic Details
Main Authors: Depatureaux, Agnès, Charpentier, Charlotte, Collin, Gilles, Leoz, Marie, Descamps, Diane, Vessière, Aurélia, Damond, Florence, Rousset, Dominique, Brun-Vézinet, Françoise, Plantier, Jean-Christophe
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935004/
https://ncbi.nlm.nih.gov/pubmed/20547806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00100-10
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