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Bioavailability and Efficacy of Levofloxacin against Francisella tularensis in the Common Marmoset (Callithrix jacchus)

Pharmacokinetic and efficacy studies with levofloxacin were performed in the common marmoset (Callithrix jacchus) model of inhalational tularemia. Plasma levofloxacin pharmacokinetics were determined in six animals in separate single-dose and multidose studies. Plasma drug concentrations were analyz...

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Detalhes bibliográficos
Main Authors: Nelson, Michelle, Lever, Mark S., Dean, Rachel E., Pearce, Peter C., Stevens, Daniel J., Simpson, Andrew J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934983/
https://ncbi.nlm.nih.gov/pubmed/20625157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00390-10
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