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Deep Brain Stimulation Alleviates Parkinsonian Bradykinesia by Regularizing Pallidal Activity

Deep brain stimulation (DBS) of the basal ganglia can alleviate the motor symptoms of Parkinson's disease although the therapeutic mechanisms are unclear. We hypothesize that DBS relieves symptoms by minimizing pathologically disordered neuronal activity in the basal ganglia. In human participa...

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Detalhes bibliográficos
Main Authors: Dorval, Alan D., Kuncel, Alexis M., Birdno, Merrill J., Turner, Dennis A., Grill, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934941/
https://ncbi.nlm.nih.gov/pubmed/20505125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00103.2010
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