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Deep Brain Stimulation Alleviates Parkinsonian Bradykinesia by Regularizing Pallidal Activity

Deep brain stimulation (DBS) of the basal ganglia can alleviate the motor symptoms of Parkinson's disease although the therapeutic mechanisms are unclear. We hypothesize that DBS relieves symptoms by minimizing pathologically disordered neuronal activity in the basal ganglia. In human participa...

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Auteurs principaux: Dorval, Alan D., Kuncel, Alexis M., Birdno, Merrill J., Turner, Dennis A., Grill, Warren M.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934941/
https://ncbi.nlm.nih.gov/pubmed/20505125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00103.2010
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