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Rationally-designed logic integration of regulatory signals in mammalian cells

Molecular-level information processing1,2, or computing, is essential for ‘smart’ in vivo nanosystems. Natural molecular computing, such as messenger RNA (mRNA) synthesis regulation by special proteins called transcription factors (TFs)3,4, may inspire engineered systems leading to the next generati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leisner, Madeleine, Bleris, Leonidas, Lohmueller, Jason, Xie, Zhen, Benenson, Yaakov
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934882/
https://ncbi.nlm.nih.gov/pubmed/20622866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2010.135
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