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IMPAIRED PRODUCTION OF BMP-15 AND GDF-9 MATURE PROTEINS DERIVED FROM PROPROTEINS WITH MUTATIONS IN THE PROREGION
Mutations in the bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9 (GDF-9) genes have been identified in women with primary ovarian insufficiency (POI) and mothers of dizygotic twins. Here, we show that biological activities of the conditioned media from human embryonic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934881/ https://ncbi.nlm.nih.gov/pubmed/20547206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2010.05.017 |
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