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Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine
Guanine deaminase (GDA; cypin) is an important metalloenzyme that processes the first step in purine catabolism, converting guanine to xanthine by hydrolytic deamination. In higher eukaryotes, GDA also plays an important role in the development of neuronal morphology by regulating dendritic arboriza...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934869/ https://ncbi.nlm.nih.gov/pubmed/20716488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.07.054 |
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