Inhibition of ICAM-1/LFA-1 Interactions Prevents B-Cell-Dependent Anti-CD45RB-Induced Transplantation Tolerance

BACKGROUND: Allogeneic tolerance can be reliably obtained with monoclonal antibody therapy targeting CD45RB. Although regulatory T cells play an important role in the mechanism, we have recently demonstrated the active participation of host B lymphocytes. After anti-CD45RB therapy, B lymphocytes dem...

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Main Authors: Huang, Xiaolun, Moore, Daniel J., Mohiuddin, Mohammad, Lian, Moh-Moh, Kim, James I., Sonawane, Samsher, Wang, Jing, Gu, Yi, Yeh, Heidi, Markmann, James F., Deng, Shaoping
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934773/
https://ncbi.nlm.nih.gov/pubmed/18337659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181663422
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