The communication between the zinc and nickel sites in dimeric HypA: Metal recognition and pH sensing

Helicobacter pylori, a pathogen that colonizes the human stomach, requires the nickel-containing metalloenzymes urease and NiFe-hydrogenase to survive this low pH environment. The maturation of both enzymes depends on the metallochaperone, HypA. HypA contains two metal sites, an intrinsic zinc site...

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Bibliografiske detaljer
Main Authors: Herbst, Robert W., Perovic, Iva, Martin-Diaconescu, Vlad, O’Brien, Kerrie, Chivers, Peter T., Pochapsky, Susan Sondej, Pochapsky, Thomas C., Maroney, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934764/
https://ncbi.nlm.nih.gov/pubmed/20662514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1005724
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