Role of NEK6 in Tumor Promoter-induced Transformation in JB6 C141 Mouse Skin Epidermal Cells

NEK6 (NIMA-related kinase 6) is a homologue of the Aspergillus nidulans protein NIMA (never in mitosis, gene A). We demonstrate that overexpression of NEK6 induces anchorage-independent transformation of JB6 Cl41 mouse epidermal cells. Tissue arrays and Western immunoblot analysis show that NEK6 is...

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Bibliographic Details
Main Authors: Jeon, Young Jin, Lee, Kun Yeong, Cho, Yong-Yeon, Pugliese, Angelo, Kim, Hong Gyum, Jeong, Chul-Ho, Bode, Ann M., Dong, Zigang
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934677/
https://ncbi.nlm.nih.gov/pubmed/20595392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137190
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