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Iron-mediated Oxidation Induces Conformational Changes within the Redox-sensing Protein HbpS

HbpS is an extracellular oligomeric protein, which has been shown to act in concert with the two-component system SenS-SenR during the sensing of redox stress. HbpS can bind and degrade heme under oxidative stress conditions, leading to a free iron ion. The liberated iron is subsequently coordinated...

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Detalhes bibliográficos
Main Authors: de Orué Lucana, Darío Ortiz, Roscher, Mareike, Honigmann, Alf, Schwarz, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934673/
https://ncbi.nlm.nih.gov/pubmed/20571030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127506
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