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Essential Molecular Determinants for Thyroid Hormone Transport and First Structural Implications for Monocarboxylate Transporter 8

Monocarboxylate transporter 8 (MCT8, SLC16A2) is a thyroid hormone (TH) transmembrane transport protein mutated in Allan-Herndon-Dudley syndrome, a severe X-linked psychomotor retardation. The neurological and endocrine phenotypes of patients deficient in MCT8 function underscore the physiological s...

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Main Authors: Kinne, Anita, Kleinau, Gunnar, Hoefig, Carolin S., Grüters, Annette, Köhrle, Josef, Krause, Gerd, Schweizer, Ulrich
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934670/
https://ncbi.nlm.nih.gov/pubmed/20628049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129577
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