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Loss of Function of Transient Receptor Potential Vanilloid 1 (TRPV1) Genetic Variant Is Associated with Lower Risk of Active Childhood Asthma

Transient receptor potential cation channels of the vanilloid subfamily (TRPV) participate in the generation of Ca(2+) signals at different locations of the respiratory system, thereby controlling its correct functioning. TRPV1 expression and activity appear to be altered under pathophysiological co...

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Detalhes bibliográficos
Main Authors: Cantero-Recasens, Gerard, Gonzalez, Juan R., Fandos, César, Duran-Tauleria, Enric, Smit, Lidwien A. M., Kauffmann, Francine, Antó, Josep M., Valverde, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934619/
https://ncbi.nlm.nih.gov/pubmed/20639579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.159491
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