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Everything you wanted to know about Markov State Models but were afraid to ask

Simulating protein folding has been a challenging problem for decades due to the long timescales involved (compared with what is possible to simulate) and the challenges of gaining insight from the complex nature of the resulting simulation data. Markov State Models (MSMs) present a means to tackle...

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Detalhes bibliográficos
Main Authors: Pande, Vijay S., Beauchamp, Kyle, Bowman, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933958/
https://ncbi.nlm.nih.gov/pubmed/20570730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.06.002
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