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LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection

POT1 is the single stranded telomeric overhang binding protein, and is part of the shelterin complex, a group of six proteins essential for proper telomere function. The reduction or abrogation of POT1 DNA binding activity in mammalian cells results in telomere elongation, or activation of the ATR D...

詳細記述

保存先:
書誌詳細
主要な著者: Sheppard, Samantha A., Loayza, Diego
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933890/
https://ncbi.nlm.nih.gov/pubmed/20634563
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