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Medial Ganglionic Eminence-derived Neural Stem Cell Grafts Ease Spontaneous Seizures and Restore GDNF Expression in a Rat Model of Chronic Temporal Lobe Epilepsy

Nearly 30% of patients with mesial temporal lobe epilepsy (TLE) are resistant to treatment with anti-epileptic drugs. Neural stem cell (NSC) grafting into the hippocampus could offer an alternative therapy to hippocampal resection in these patients. As TLE is associated with reduced numbers of inhib...

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Autores principales: Waldau, Ben, Hattiangady, Bharathi, Kuruba, Ramkumar, Shetty, Ashok K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933789/
https://ncbi.nlm.nih.gov/pubmed/20506409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.446
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