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Fold Homology Detection Using Sequence Fragment Composition Profiles of Proteins
The effectiveness of sequence alignment in detecting structural homology among protein sequences decreases markedly when pairwise sequence identity is low (the so-called “twilight zone” problem of sequence alignment). Alternative sequence comparison strategies able to detect structural kinship among...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933786/ https://ncbi.nlm.nih.gov/pubmed/20635424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22788 |
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