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Activation of NMDA receptors in the brainstem, RVM and NGC, mediates mechanical hyperalgesia produced by repeated intramuscular injections of acidic saline in rats

Repeated injections of acidic saline into the gastrocnemius muscle induced both muscle and cutaneous hypersensitivity. We have previously shown that microinjection of local anesthetic into either the rostral ventromedial medulla (RVM) or the nucleus reticularis gigantocellularis (NGC) reverses this...

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Bibliografiske detaljer
Main Authors: Da Silva, LFS, DeSantana, JM, Sluka, KA
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933661/
https://ncbi.nlm.nih.gov/pubmed/19853525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2009.08.006
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