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Sample Size Calculation in Clinical Trials: Part 13 of a Series on Evaluation of Scientific Publications

BACKGROUND: In this article, we discuss the purpose of sample size calculation in clinical trials, the need for it, and the methods by which it is accomplished. Study samples that are either too small or too large are unacceptable, for clinical, methodological, and ethical reasons. The physicians pa...

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Autors principals: Röhrig, Bernd, du Prel, Jean-Baptist, Wachtlin, Daniel, Kwiecien, Robert, Blettner, Maria
Format: Artigo
Idioma:Inglês
Publicat: Deutscher Arzte Verlag 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933537/
https://ncbi.nlm.nih.gov/pubmed/20827353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3238/arztebl.2010.0552
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