Dedifferentiation and Proliferation of Mammalian Cardiomyocytes

BACKGROUND: It has long been thought that mammalian cardiomyocytes are terminally-differentiated and unable to proliferate. However, myocytes in more primitive animals such as zebrafish are able to dedifferentiate and proliferate to regenerate amputated cardiac muscle. METHODOLOGY/PRINCIPAL FINDINGS...

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Detalhes bibliográficos
Main Authors: Zhang, Yiqiang, Li, Tao-Sheng, Lee, Shuo-Tsan, Wawrowsky, Kolja A., Cheng, Ke, Galang, Giselle, Malliaras, Konstantinos, Abraham, M. Roselle, Wang, Charles, Marbán, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933247/
https://ncbi.nlm.nih.gov/pubmed/20838637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012559
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