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T-cell Acute Lymphoblastic Leukemia in Association with Börjeson-Forssman-Lehmann Syndrome Due to a Mutation in PHF6

Börjeson-Forssman-Lehmann syndrome (BFLS) is a rare X-linked mental retardation syndrome that is caused by germline mutations in PHF6. We describe a 9-year old male with BFLS, who developed T-cell acute lymphoblastic leukemia (T-ALL). The PHF6 gene is located on the X chromosome and encodes a protei...

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Detalhes bibliográficos
Main Authors: Chao, Mwe Mwe, Todd, Matthew A., Kontny, Udo, Neas, Katherine, Sullivan, Michael J., Hunter, Alasdair G., Picketts, David J., Kratz, Christian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933084/
https://ncbi.nlm.nih.gov/pubmed/20806366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22574
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