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Bipartite Adenoviral Vector encoding hHGF and hIL-1Ra for Improved Human Islet Transplantation
PURPOSE: Ex vivo gene therapy can improve the outcome of islet transplantation for treating type I diabetes. Hepatocyte growth factor (HGF) increases β-cell proliferation and promotes revascularization of islets, while interleukin-1 receptor antagonist (hIL-1Ra) inhibits islet cell apoptosis. METHOD...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933074/ https://ncbi.nlm.nih.gov/pubmed/19002565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9777-y |
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