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Thionate versus Oxon: A Comparison of Stability, Uptake, and Cell Toxicity of ((14)CH(3)O)(2)-Labeled Methyl Parathion and Methyl Paraoxon with SH-SY5Y Cells

The stability, hydrolysis and uptake of the organophosphates methyl parathion and methyl paraoxon were investigated in SH-SY5Y cells. The stabilities of ((14)CH(3)O)(2)-methyl parathion ((14)C-MPS) and (14)C-methyl paraoxon ((14)C-MPO) at 1 μM in culture media had similar half lives of 91.7 h and 10...

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Main Authors: Bharate, Sandip B., Prins, John M., George, Kathleen M., Thompson, Charles M.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932872/
https://ncbi.nlm.nih.gov/pubmed/20590114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf100976v
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