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Metallomic Analysis of Macrophages Infected with Histoplasma capsulatum Reveals a Fundamental Role for Zn in Host Defenses
The fungal pathogen Histoplasma capsulatum evades the innate and adaptive immune responses and thrives within resting macrophages (Mφ). Cytokines that induce antimicrobial activity such as granulocyte macrophage-colony stimulating factor (GM-CSF) inhibit H. capsulatum growth in Mφ. Conversely, inter...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932870/ https://ncbi.nlm.nih.gov/pubmed/20731582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/656191 |
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