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Pnpla3/adiponutrin deficiency in mice is not associated with fatty liver disease

PNPLA3 (Adiponutrin), a novel patatin-like phospholipase domain-containing enzyme, is expressed at high level in fat, but also in other tissues including liver. Polymorphisms in PNPLA3 have been linked to obesity and insulin sensitivity. Notably, a nonsynonymous variant rs738409(G) allele of the PNP...

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Hlavní autoři: Chen, Weiqin, Chang, Benny, Li, Lan, Chan, Lawrence
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932863/
https://ncbi.nlm.nih.gov/pubmed/20648554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23812
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