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High-Fructose Medium-Chain-Trans-Fat Diet Induces Liver Fibrosis & Elevates Plasma Coenzyme Q9 in a Novel Murine Model of Obesity and NASH

Diets high in saturated fat and fructose have been implicated in the development of obesity and nonalcoholic steatohepatitis (NASH) in humans. We hypothesized that mice exposed to a similar diet would develop NASH with fibrosis associated with increased hepatic oxidative stress that would be further...

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Main Authors: Kohli, Rohit, Kirby, Michelle, Xanthakos, Stavra A., Softic, Samir, Feldstein, Ariel E., Saxena, Vijay, Tang, Peter H., Miles, Lili, Miles, Michael V., Balistreri, William F., Woods, Stephen C., Seeley, Randy J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932817/
https://ncbi.nlm.nih.gov/pubmed/20607689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23797
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