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Induction of pre-B cell proliferation after de novo synthesis of the pre-B cell receptor

The assembly of a pre-B cell receptor (pre-BCR) composed of an Ig μ heavy chain (μH-chain), the surrogate light (SL) chain, and the Igα/β dimer is critical for late pro-B cells to advance to the pre-B cell stage. By using a transgenic mouse model, in which μH-chain synthesis is solely driven by a te...

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Bibliographische Detailangaben
Hauptverfasser: Hess, Jochen, Werner, Annick, Wirth, Thomas, Melchers, Fritz, Jäck, Hans-Martin, Winkler, Thomas H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC29328/
https://ncbi.nlm.nih.gov/pubmed/11172022
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