Identifying Regulators for EAG1 Channels with a Novel Electrophysiology and Tryptophan Fluorescence Based Screen

BACKGROUND: Ether-à-go-go (EAG) channels are expressed throughout the central nervous system and are also crucial regulators of cell cycle and tumor progression. The large intracellular amino- and carboxy- terminal domains of EAG1 each share similarity with known ligand binding motifs in other prote...

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Huvudupphovsmän: Brelidze, Tinatin I., Carlson, Anne E., Davies, Douglas R., Stewart, Lance J., Zagotta, William N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932742/
https://ncbi.nlm.nih.gov/pubmed/20824064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012523
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