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Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis

Chromosomal instability and the subsequent genetic mutations are considered to be critical factors in the development of the majority of solid tumors. Here, we describe how the nucleoside diphosphate kinase Nm23-H1, a protein with a known link to cancer progression, regulates a critical step during...

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Autori principali: Conery, Andrew R., Sever, Sanja, Harlow, Ed
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932595/
https://ncbi.nlm.nih.gov/pubmed/20713695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010633107
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